Diabetes mellitus exacerbates cardiovascular remodeling in elderly Chinese by affecting aortic diameter and pulsatile load.

ABSTRACT: Cardiovascular health is negatively impacted by arterial stiffening, which increases pulsatile load and elevates left ventricular workload. Aortic dilatation may compensate for the pulsatile overload resulting from arterial stiffening. Previous studies have shown a negative correlation between diabetes and aortic diameter, suggesting that diabetes may impair aortic dilatation and thereby compromise compensatory buffering capacity. This study aims to explore the relationship between diabetes, aortic diameter, and left ventricular hypertrophy. This retrospective study included 271 elderly patients stratified by diabetes status. Aortic and cardiac geometry was measured via echocardiography, and arterial stiffness was assessed using brachial-ankle pulse wave velocity (baPWV). Pulse pressure (P

SUBMITTER: Jiang Y 

PROVIDER: S-EPMC12402055 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature