Severe Diffuse Takayasu Arteritis Manifestation in Childhood.

ABSTRACT:

Background

Takayasu arteritis (TA) is a large-vessel vasculitis that primarily affects the aorta and the pulmonary and coronary arteries.

Case summary

A 4-year-old boy was diagnosed in 2022 with pyoderma gangrenosum (PG) and required prolonged multidisciplinary care, including aggressive medical immunosuppression for severe skin lesions. In October 2024, after a period of clinical stability, he presented with a seizure and right-sided weakness. Head and neck computed tomography angiography revealed features of acute inflammatory vasculitis. These findings along with clinical criteria led to a diagnosis of TA. Vascular imaging (echocardiogram, computed tomography, magnetic resonance imaging) showed diffuse disease affecting the aortic root, aortic arch, proximal supra-aortic

SUBMITTER: Cano de Santayana Dominguez ME 

PROVIDER: S-EPMC12402393 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature