A Multicenter, Retrospective Analysis of Long-Term Survival in 255 Dogs With Pheochromocytoma Treated With Alpha-Adrenoreceptor Antagonists or Surgery (2010-2021).

ABSTRACT:

Background

The survival of dogs with pheochromocytoma (PCC) treated with adrenoreceptor antagonists has not been described or compared to surgically managed cases.

Hypothesis/objectives

The objective of this study is to evaluate the survival of medically and surgically managed dogs with PCC and investigate factors associated with survival.

Animals

Two hundred fifty-five dogs with PCC, treated with alpha-adrenoreceptor antagonists (AA) without adrenalectomy (Group 1, n = 75), adrenalectomy +/- AA (Group 2, n = 128), or neither treatment (Group 3, n = 52).

Methods

Retrospective, multicenter review of medical records. Median overall survival time (OST) for Groups 1 and 2 combined was calculated using Kaplan-Meier estimates, and then compared between Group 1 and Gr

SUBMITTER: Steele MME 

PROVIDER: S-EPMC12402397 | biostudies-literature | 2025 Sep-Oct

REPOSITORIES: biostudies-literature