Pathological beta power increase in the subthalamic nucleus is absent in essential tremor.

ABSTRACT: Parkinson's disease and essential tremor are common movement disorders characterized by distinct motor symptoms. Deep brain stimulation targeting the subthalamic nucleus has shown efficacy in managing Parkinson's disease symptoms, whereas the posterior subthalamic area is an emerging target for essential tremor. This analytical cross-sectional study investigates the electrophysiological activity of the subthalamic nucleus in Parkinson's disease and essential tremor patients from deep brain stimulation surgeries to understand the underlying neural oscillatory mechanisms. Microelectrode recordings during deep brain stimulation surgery from 35 Parkinson's disease patients targeting the subthalamic nucleus and 21 essential tremor patients simultaneously targeting the posterior subthalamic area

SUBMITTER: Baker Erdman H 

PROVIDER: S-EPMC12402545 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature