A nomogram for predicting the risk of chemoradiotherapy-associated thrombocytopenia in patients with esophageal cancer: a real-world cohort study.

ABSTRACT:

Background

Thrombocytopenia is a common hematological toxicity in esophageal cancer (EC) patients receiving radiation therapy.

Objectives

The purpose of this study was to construct and validate a nomogram for predicting the incidence of thrombocytopenia in EC patients receiving radiotherapy.

Design

A retrospective study.

Methods

All data were collected from 435 EC patients who received radiation therapy from a real-world cohort study from 2016 to 2021. Thrombocytopenia was assessed according to the toxicity criteria of the Radiation Therapy Oncology Group (RTOG). Univariate and multivariate logistic regression analyses were used to identify significant risk factors for thrombocytopenia. The result was presented in the form of a nomogram. The performance of the

SUBMITTER: Yang JX 

PROVIDER: S-EPMC12402651 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature