Uncovering the Understanding of the Concept of Patient Similarity in Cancer Research and Treatment: Scoping Review.

ABSTRACT:

Background

Patient similarity is a fundamental concept in precision oncology, offering a pathway to personalized medicine by identifying patterns and shared characteristics among patients. This concept enables stratification into clinically meaningful subgroups, prediction of treatment responses, and the tailoring of therapeutic interventions to individual needs. Despite its transformative potential, the definition, measurement, and clinical application of patient similarity remain inconsistently established, creating challenges in its integration into cancer research and clinical practice.

Objective

This study aimed to synthesize evidence on the multidimensional concept of patient similarity in cancer research by analyzing its application across different points of possible

SUBMITTER: Manuilova I 

PROVIDER: S-EPMC12402742 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature