Sex Differences in the Association Between Physical Functioning and Cognition in Two Central European Populations.

ABSTRACT:

Background

Evidence on the relationship between physical and cognitive functions remains inconsistent, and the role of sex differences is underexplored. This study examines the predictive value of a composite Physical Functioning Score (PFS) for cognitive function and assesses sex-specific associations in an Eastern European population.

Methods

Data from 7309 participants (mean age 59 ± 7.3 years) from the Czech Republic and Poland arms of the HAPIEE study were analyzed. PFS was derived from a 23-item measure including activity of daily living (ADL/IADL), grip strength, functional limitations, and physical activity. Cognitive function was assessed using standardized tests of memory, verbal fluency, and speed/concentration. Logistic regression, adjusted for demographic, lifes

SUBMITTER: Court T 

PROVIDER: S-EPMC12402904 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature