Association Between Dietary Niacin Intake and Life's Essential 8 Among US Adults (NHANES 2005-2018).

ABSTRACT: Limited evidence exists on the relationship between dietary niacin intake and Life's Essential 8 (LE8), a new metric for cardiovascular health. We analyzed data from 23,729 adults aged ≥ 20 years from the 2005-2018 National Health and Nutrition Examination Survey (NHANES). The LE8 score (range: 0-100) reflects health behaviors, health factors, and biomarkers. After adjusting for confounders, each 10-unit increase in niacin intake was associated with 0.65-point higher LE8 score (β = 0.65, 95% CI = 0.43-0.87; p < 0.001). Compared to the lowest tertile, the highest tertile of niacin intake had a 1.83-point higher LE8 score (β = 1.83, 95% CI = 1.02-2.64; p < 0.001). Restricted cubic spline analysis indicated a linear dose-response relationship (P-nonlinearity = 0.57

SUBMITTER: Wang D 

PROVIDER: S-EPMC12402905 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature