A nomogram for predicting post-stroke cognitive impairment no dementia in patients with first-ever mild ischemic stroke.

ABSTRACT:

Objective

To identify significant predictors and construct a validated nomogram for predicting post-stroke cognitive impairment no dementia (PSCIND) risk among first-ever mild ischemic stroke (MIS) patients.

Methods

This retrospective cohort study analyzed 242 first-ever MIS patients categorized into normal cognitive (n = 137) and PSCIND (n = 105) groups. Comprehensive data encompassing demographic characteristics, laboratory parameters, cerebral small vessel disease (CSVD) imaging markers, neuropsychological assessments, and ischemic stroke lesion characteristics were collected. Predictor selection was conducted through least absolute shrinkage and selection operator (LASSO) regression analysis, followed by multivariable logistic regression for nomogram constr

SUBMITTER: Teng Z 

PROVIDER: S-EPMC12402937 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature