Landscape changes elevate the risk of avian influenza virus diversification and emergence in the East Asian-Australasian Flyway.

ABSTRACT: Highly pathogenic avian influenza viruses (HPAIV) persistently threaten wild waterfowl, domestic poultry, and public health. The East Asian-Australasian Flyway plays a crucial role in HPAIV dynamics due to its large populations of migratory waterfowl and poultry. Over recent decades, this flyway has undergone substantial landscape changes, including both losses and gains of waterfowl habitats. These changes can affect waterfowl distributions, increase contact with poultry, and consequently alter ecological conditions that favor avian influenza virus (AIV) evolution. However, limited research has assessed these likely impacts. Here, we integrated empirical data and an individual-based model to simulate AIV transmission in migratory waterfowl and domestic poultry, including wild-to-poultry s

SUBMITTER: Yin S 

PROVIDER: S-EPMC12403075 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature