Metabolomics navigates natural variation in pathogen-induced secondary metabolism across soybean cultivar populations.

ABSTRACT: Phytophthora sojae-induced root rot poses a major threat to soybean production. While the molecular mechanisms underlying soybean-P. sojae interactions have been extensively studied, their biochemical basis remains largely unexplored. Previous research has identified key metabolic modules involved in pathogen defense, but structural diversity has largely been constrained by studies on single soybean accessions. Here, we broadened the chemical search space to a diverse soybean germplasm collection using high-throughput metabolomics as a powerful tool for comprehensive metabolic profiling. Chemical classes of lipids and phenylpropanoids again retrieved the most pronounced responses upon P. sojae infection in general. A two-layer analytical strategy further finely resolve

SUBMITTER: Tian M 

PROVIDER: S-EPMC12403127 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature