Deciphering metabolic regulation in overripe grapes through multi-omics analysis of non-targeted metabolome, proteome, and transcriptome.

ABSTRACT:

Background

As climate warms, the sugars and secondary metabolites in grapes gradually become uncoupled during development, resulting in the phenomenon of overripe fruit becoming more frequent around the world, especially in some arid regions. However, the key metabolic regulations to grape overripening are still poorly understood. To address this, we conducted a multi-omics study on Cabernet Sauvignon overripe berries over two years, analyzing the non-targeted metabolome, transcriptome, and proteome, aiming to provide a theoretical basis for delayed harvest strategies based on grape quality.

Results

The delayed harvests caused significant changes in berry transcriptome and proteome. Genes and proteins responding to environmental changes were up-regulated, while those related

SUBMITTER: Shi N 

PROVIDER: S-EPMC12403331 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature