Prognostic value of risk factors in cervical squamous cell carcinoma based on tumour infiltration depth.

ABSTRACT:

Objective

To evaluate whether the prognostic significance of distinct risk factors differs according to tumour infiltration depth in cervical squamous cell carcinoma.

Methods

We performed a retrospective cohort study of 621 patients treated at our institution between June 2012 and March 2019. Postoperative histopathological evaluation classified patients into two groups: Group 1 (n = 321) demonstrated complete full-thickness infiltration (100%) of the cervical stromal wall, whereas Group 2 (n = 320) exhibited partial stromal infiltration (≤ 80%).

Results

Multivariate Cox regression survival analysis revealed that tumour volume(gTV) > 30.8 cm³, lymph node metastasis(gLNM), and vaginal invasion(gVI) were independent prognostic factors for 5-year survival in Group 1 (all

SUBMITTER: Yang Q 

PROVIDER: S-EPMC12403517 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature