Critical genomic insights into vancomycin-resistant <i>Enterococcus faecium</i> in Lebanon.

ABSTRACT: Vancomycin-resistant Enterococcus faecium (VRE) poses a global public health threat, with particularly severe ramifications in low-resource settings. While E. faecium is commonly a commensal organism in the human gut, the acquisition of vancomycin resistance has contributed to the emergence of VRE as a major cause of hospital-acquired infections, especially in vulnerable populations. This study investigates the genetic characteristics of VRE isolated from hospitalized patients in Lebanon, focusing on antimicrobial resistance (AMR) phenotypes and the underlying resistome. We collected VRE isolates from patients at the time of admission or during routine screenings for multidrug-resistant pathogens. The isolates were identified using matrix-assisted laser desorption/ionization

SUBMITTER: Osman M 

PROVIDER: S-EPMC12403557 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature