The regulatory network of <i>Coprinopsis cinerea</i> transcription factor Skn7 collaborates with bHLH1 during fungal-fungal interactions.

ABSTRACT: Fungal-fungal interactions have attracted increasing attention due to alterations in physiological and developmental patterns and the upregulation of secondary metabolites. However, the molecular mechanisms underlying this phenomenon remain poorly understood. Previously, we reported that intracellular reactive oxygen species (ROS) function as signal molecules to induce defense responses in a basidiomycete fungus, Coprinopsis cinerea, against a Mucoromycete fungus Gongronella butleri w5, concomitant with the upregulation of Skn7, a regulator participating in oxidative stress response. In this study, gene silencing and overexpression experiments demonstrated the involvement of Skn7 in mycelial growth and antioxidation in C. cinerea during cocultivation. According to the

SUBMITTER: Zhao H 

PROVIDER: S-EPMC12403569 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature