Hypervirulent <i>Klebsiella pneumoniae</i> causing bloodstream infections in Hungary.

ABSTRACT: Hypervirulent Klebsiella pneumoniae (hvKP) can cause severe infections even in healthy individuals. Currently, no data are available on the frequency of hvKP-induced bloodstream infections (BSI) in Hungary. Our investigation revealed that of the 157 K. pneumoniae isolated from BSI in 2020-2022 at a university hospital in Hungary, three (2%) carried the hypervirulence-associated rmpA and iutAiucABCD genes. The complete genomes of these three hvKP isolates were sequenced. They were unrelated and belonged to ST5, ST86, and ST6771, a single-locus variant of ST893, i.e., to internationally known hvKP clones. In the K. pneumoniae ST86 and ST6771 isolates, the rmpA/A2, aerobactin, and salmochelin siderophore genes were located on virulence plasmids

SUBMITTER: Mohamed FA 

PROVIDER: S-EPMC12403626 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature