Investigating the impact of the COVID-19 pandemic on pediatric adenovirus infection patterns: a retrospective analysis.

ABSTRACT: This study aimed to compare the epidemiological features and clinical manifestations of adenovirus (ADV)-associated pediatric respiratory tract infections during and after the lockdown due to coronavirus disease 2019 (COVID-19) pandemic to explore potential immunity debt. A retrospective analysis was conducted to evaluate ADV detection rates, co-infection rates, serotype distribution, age distribution of infected children, proportions of mild, moderate, and severe ADV pneumonia cases, and relevant laboratory indicators (e.g., white blood cell count, granulocyte-to-lymphocyte ratio, high-sensitivity C-reactive protein, and lactate dehydrogenase) during and after the lockdown. Post-lockdown ADV detection and co-infection rates were significantly higher than those during the lockdown (P

SUBMITTER: Gu Y 

PROVIDER: S-EPMC12403655 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature