Clinical characteristics and efficacy of short-course antibiotic therapy for <i>Staphylococcus aureus</i> bacteremia in hematological patients.

ABSTRACT: To explore the clinical characteristics and outcomes of Staphylococcus aureus bacteremia (SAB) in patients with hematological diseases and evaluate the efficacy of short-course antibiotic therapy for uncomplicated SAB in this group. We performed a retrospective study on hematological adult patients with SAB, including a high proportion of neutropenic patients. Logistic regression models fitted with inverse probability of treatment weighting were employed to evaluate the association between treatment duration and clinical outcomes in patients with uncomplicated SAB. A total of 242 patients infected with SAB were included, of whom 38 (15.7%) were caused by MRSA. The 90-day mortality and 30-day mortality rate were 11.2% (n = 27) and 4.5% (n = 11), respectively, while the

SUBMITTER: Yang N 

PROVIDER: S-EPMC12403743 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature