Comparative mitogenomics reveals evolutionary drivers of Strongyloidea nematodes dwelling in gastrointestinal tract.

ABSTRACT:

Background

The nematode superfamily Strongyloidea represents a prevalent group of gastrointestinal parasites in ruminants and livestock, posing substantial veterinary and economic burdens worldwide. Here we present the first mitochondrial genomic investigation for reconstructing Strongyloidea phylogeny and investigating niche-specific selection dynamics across gastrointestinal habitats (abomasum, small intestine, and large intestine). This study presents a preliminary exploration of the evolutionary adaptations of these agriculturally relevant parasites through comprehensive mitogenomic analysis.

Results

Phylogenomic reconstruction revealed strong anatomical clustering with high nodal support. Comparative synteny analyses revealed conserved mitogenome architectures across St

SUBMITTER: Li J 

PROVIDER: S-EPMC12403925 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature