Genomic analysis of <i>Streptococcus canis</i> from different hosts in Italy 2004-2021: diversity, antimicrobial resistance, and virulence profiles.

ABSTRACT: Streptococcus canis, a multi-host pathogen commonly isolated from dogs and cats has been occasionally reported in severe cases of human infection. This study aimed to explore the genetic diversity, antimicrobial resistance (AMR), and pathogenicity of S. canis isolates collected between 2004-2021, in Italy. Fifty-five S. canis isolates from clinical cases in domestic animals were investigated for susceptibility to antibiotics and then characterized for sequence type (ST), virulence profile, and antimicrobial-resistant genes through whole genome sequencing (WGS). All isolates were susceptible to beta-lactams, while frequently exhibiting resistance to lincosamides, chlortetracyclines, and macrolides. Six out of 55 isolates of S. canis, all collected between 2020 an

SUBMITTER: Cucco L 

PROVIDER: S-EPMC12404155 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature