Validation of a parent-reported outcome measure for young boys with a condition affecting sex development (PRO-CSD).

ABSTRACT:

Objective

To validate a short parent-reported outcome (PRO) questionnaire in young boys with conditions affecting sex development (PRO-CSD).

Design

Consecutive sample cross-sectional study.

Setting

A single tertiary children's hospital in Glasgow, UK.

Patients

A total number of 98 parents of 98 affected boys with a median age of 3.1 years (10th, 90th: 0.7, 5.4).

Interventions

Completion of recently developed brief PRO-CSD consisting of a parent proxy-report (PPR) and a parent self-report (PSR).

Main outcomes

The study assessed test-retest reliability in 41 cases as intraclass correlation coefficients (ICCs) and group construct validity in 98 by exploring associations with seven demographic and clinical features.

Results

The median ICC for a

SUBMITTER: Tseretopoulou X 

PROVIDER: S-EPMC12404183 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature