Low-dose calcium supplementation during pregnancy in low and middle-income countries: A cost-effectiveness analysis.

ABSTRACT: Calcium supplementation during pregnancy can reduce the risk of preeclampsia and preterm birth. Few countries have implemented WHO-recommended high-dose calcium supplementation (1500-2000mg/day), due to adherence and cost concerns. However, low-dose calcium supplementation (one 500mg tablet daily) has recently been shown to be similarly efficacious as high-dose supplementation. We assessed the cost-effectiveness of low-dose calcium supplementation during pregnancy, in low- and middle-income countries (LMICs) with low dietary calcium intake. To do so, we conducted a mathematical modelling analysis in which we estimated the lifetime health outcomes (cases, deaths, and DALYs averted) and costs of low-dose calcium supplementation provided through routine antenatal care to women giving birth in

SUBMITTER: Saronga HP 

PROVIDER: S-EPMC12404394 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature