Efficacy of Pulsatilla saponin B4 for treatment dairy cows affected with clinical mastitis.

ABSTRACT: In order to explore the therapeutic effect of natural compound Pulsatilla saponin B4 (PSB4) on clinical mastitis (CM) in dairy cows, 40 dairy cows with CM and 20 healthy dairy cows were selected as experimental samples in a large dairy farm. The CM cows were randomly divided into two groups (20 cows in each group), namely the PSB4 group treated with PSB4 neck intramuscular injection and the positive drug (PC) group treated with ceftiofur sodium neck intramuscular injection as a positive control. Another 20 healthy dairy cows were neck intramuscular injected with the same amount of normal saline to serve as a normal control (NC) group. The treatment duration was 7 days. The body temperature and milk yield of all cows were recorded on days 0, 4 and 7, while blood and milk samples were collec

SUBMITTER: Zhang H 

PROVIDER: S-EPMC12404452 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature