Epidemiological trends and projections to 2035 of hepatitis B burden in China, 1990-2021.

ABSTRACT:

Background

Hepatitis B virus (HBV) remains a major cause of liver disease and premature death globally, with China bearing a significant share of the burden. However, long-term trends and future projections of HBV burden in China remain insufficiently described, despite widespread infant vaccination and expanded antiviral therapy.

Methods

We analyzed hepatitis B-related mortality, age-standardized mortality rate (ASMR), disability-adjusted life years (DALYs), and age-standardized DALY rate (ASDR) in China from 1990 to 2021 using data extracted from the GBD 2021 database. Temporal trends were quantified by estimated annual percentage change (EAPC).

Results

Between 1990 and 2021, the number of deaths from hepatitis B-related liver diseases in China increased from 215 th

SUBMITTER: Qi X 

PROVIDER: S-EPMC12404462 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature