Relationship between pulse wave velocity progression and baseline heart rate and its change over 3.7 years of follow-up in hypertensive patients.

ABSTRACT:

Objective

The role of resting heart rate (HR) and of its changes over time on the progression of pulse wave velocity (PWV) has not been extensively evaluated. The aim of this study was to investigate this relationship in a population of hypertensive patients in a longitudinal study.

Methods

We enrolled 572 hypertensive outpatients aged 18-80, followed by the Hypertension Unit of St. Gerardo Hospital (Monza, Italy). Anamnestic, clinical and laboratory data, BP and PWV were assessed at baseline and after a median follow-up of 3.7 ± 0.5 years.

Results

At baseline, mean age was 53.9 ± 12.7 years, SBP and DBP were 141.2 ± 17.8 and 86.5 ± 10.5 mmHg, HR was 65.6 ± 10.9 bpm and PWV was 8.6 ± 2.0 m/s. Despite an improvement in BP and therapies, at follow-up, a PWV increase (ΔP

SUBMITTER: Maloberti A 

PROVIDER: S-EPMC12404624 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature