Revealing hyperactivated IFN-γ pathways in perianal fistulizing Crohn's disease using single-cell and spatial multi-omics.

ABSTRACT: Up to 40% patients with Crohn's disease suffer from perianal disease, a debilitating complication with unclear etiology. This study identified unique pathophysiology which may help develop novel therapies.

SUBMITTER: Cao S 

PROVIDER: S-EPMC12404762 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature