Knee Extensor Structure and Function in Children, Adolescents, Adults, and Older Adults With Obesity: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objective

This study aims to evaluate the association between obesity and both absolute and relative measures of knee extensor muscle structure and contractile function across different age groups, including children, adolescents, adults, and older adults.

Methods

A search for potential studies was performed in four electronic databases. Data were meta-analyzed using a random-effects model for our primary outcomes of knee extensor structure (muscle size and quality) and function (maximal force/torque, rapid torque, and fatigue) and compared between those with or without obesity in each age group.

Results

The findings indicate that obesity significantly increases absolute measures of knee extensor maximal contractile function and muscle size. However, obesity was assoc

SUBMITTER: Vakula MN 

PROVIDER: S-EPMC12404886 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature