Glucose and lipid metabolism in non-diabetic, non-obese patients with obstructive sleep apnea: sex differences.

ABSTRACT:

Objective

Obstructive sleep apnea (OSA) is associated with glucose and lipid disturbances and insulin resistance. However, glucose and lipid disturbances and insulin resistance in OSA are often attributed to confounding obesity and/or diabetes. Studies on nondiabetic, nonobese OSA patients are very limited.

Methods

This cross-sectional study retrospectively analyzed non-diabetic, non-obese adults who underwent a home sleep apnea testing and collected fasting blood samples before or after the sleep study to measure glucose and lipids. This study was designed as a cross-sectional study and therefore can only demonstrate associations between variables, but not causality.

Results

Among the 191 participants (mean age 48.94 years, 68.06% male) included in the study, 83.77%

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12404915 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature