Quantitative histopathologic profiling of arterial dissection-related thrombi in acute ischemic stroke: etiological comparisons.

ABSTRACT:

Introduction

Arterial dissection is an important etiology of stroke in young adults and may demonstrate distinct thrombus characteristics. While most studies have focused on compositional differences between cardioembolic (CE) and non-cardioembolic thrombi, systematic analyses of dissection-related thrombi remain scarce. This study characterized the compositions of dissection thrombi, compared them with those of non-dissection thrombi, and explored compositional variations among stroke etiologies.

Materials and methods

We retrospectively analyzed the clinical data and thrombi of 230 patients with acute ischemic stroke (AIS). The thrombi were stained with hematoxylin and eosin (H&E) and digitally scanned, and their composition was analyzed based on quantified red blood cell (

SUBMITTER: Cai G 

PROVIDER: S-EPMC12404956 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature