Case Report: A patient with an empty sella accompanied by rare thyrotoxicosis.

ABSTRACT: Empty sella (ES) involves herniation of the pituitary fossa, leading to pituitary flattening. While typically associated with central hypothyroidism, its co-occurrence with hyperthyroidism is rarely reported and often overlooked. We report a rare case of hyperthyroidism in a patient with ES. The patient was diagnosed with ES combined with Graves' disease (GD) and Hashimoto's thyroiditis (HT). Her pituitary gland appeared flattened with a depressed upper edge. The gland height was approximately 2.3 mm. Abnormal thyroid function in this case may result from the combined effects of all three conditions. A literature search on PubMed revealed a possible association between ES and autoimmune thyroid disease; however, only seven relevant studies were identified, and no standardized diagnostic or

SUBMITTER: Li Z 

PROVIDER: S-EPMC12404976 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature