A prognostically meaningful definition of non-dilated left ventricular cardiomyopathy.

ABSTRACT: Non-dilated left ventricular cardiomyopathy (NDLVC) has been defined as non-ischemic LV scarring and/or fatty replacement and/or hypokinesia, without LV dilation. We tried to identify specific criteria for LV dilation and dysfunction to implement this definition. We identified all non-ischemic cardiomyopathy patients undergoing a cardiovascular magnetic resonance scan from 2012 to 2022 with LV ejection fraction (LVEF) < 55% and/or non-ischemic late gadolinium enhancement (LGE) and/or fatty replacement, and without specific etiologies. The primary endpoint was a composite of all-cause death, sustained ventricular tachycardia or fibrillation. The cohort included 388 patients (32% women, median age 55 years [interquartile range 43-63]). Over 4.3 years (1.9-7.0), 59 patients (15%) developed a

SUBMITTER: Aimo A 

PROVIDER: S-EPMC12405037 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature