Comprehensive Metabolomic Profiling and Biological Activity Analysis of <i>Eschscholzia californica</i> Extracts Using LC-ESI-QTOF-MS.

ABSTRACT: The current investigation was designed to explore the chemical composition, antioxidant capacity, enzyme inhibitory activity, and cytotoxic potential of four different extracts (Ethyl Acetate, Ethanol, Ethanol/Water (70%) and Water) derived from the aerial parts of Eschscholzia californica. In vitro, assessments were performed utilizing diverse antioxidant assays, along with evaluations of neuroprotective enzyme inhibition targeting acetylcholine and butyl choline enzymes, as well as antidiabetic activities against α-amylase and α-glucosidase and a potential candidate for a tyrosinase inhibitor. LC-ESI-QTOF-MS identification provided a total of 70 compounds in the extracted samples of E. californica, including kaempferol 3-(deoxyhexosyl-hexoside)-7-hexoside, rutin, quercetin

SUBMITTER: Kalyniukova A 

PROVIDER: S-EPMC12405063 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature