Effect of Preoperative Budesonide on Postoperative Sore Throat: A Systematic Review and Meta-Analysis.

ABSTRACT: Background: Postoperative sore throat (POST) is a common complication following endotracheal intubation. Various pharmacological interventions have been explored for POST prevention, with budesonide emerging as a promising option due to its anti-inflammatory properties. Methods: PubMed, Scopus, Web of Science and the Cochrane Library were searched following PRISMA guidelines. The primary outcomes were POST incidence and severity. Incidence data were pooled using random- or fixed-effects models. Severity analysis focused on budesonide versus saline studies, applying an ordinal logistic regression (mild, moderate, severe) with group assignment as the predictor, and predicted probabilities were computed in R. Results: Budesonide significantly reduced the incidence of POST

SUBMITTER: Metwalli H 

PROVIDER: S-EPMC12405198 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature