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Prediction of Motor Recovery after Subacute Cerebral Infarction: Role of Corticocerebellar Pathway Integrity.


ABSTRACT: BackgroundThe cerebellar cortex has gradually become a promising therapeutic target for improving motor recovery post-cerebral infarction, potentially dependent on the structural integrity of motor-related corticocerebellar pathways (CCP). However, the relationship between the imaging markers of motor-related CCP and motor prognosis remains inadequately explored. Utilizing diffusion tensor imaging (DTI), this study aims to longitudinally assess the role of motor-related CCP in predicting motor recovery for both upper and lower extremities following cerebral infarction.MethodsTwenty-nine patients with right middle cerebral artery (MCA) infarction underwent 2 DTI scans 7 to 14 and 30 days after onset, and 29 age-sex matched controls received 1 scan. Fractional anisotropy (FA) values were mea

SUBMITTER: Liu J 

PROVIDER: S-EPMC12405655 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature