Contribution of Peripheral Airways Dysfunction to Poor Quality of Life in Sarcoidosis.

ABSTRACT:

Background

Sarcoidosis is characterized by reduced quality of life (QoL), yet QoL is correlated poorly to conventional spirometric lung function tests.

Research question

What is the relationship of a QoL measure with comprehensive lung function assessment using oscillometry in sarcoidosis?

Study design and methods

Sixty-two patients with pulmonary sarcoidosis completed the St. George's Respiratory Questionnaire (SGRQ), a respiratory QoL measure, and underwent lung function assessment including oscillometry, spirometry, diffusion capacity, fractional exhaled nitric oxide (Feno), and body plethysmography. Relationships of lung function parameters with SGRQ results were determined with Spearman rank coefficient (ρ), and receiver operating characteristic curves were plott

SUBMITTER: Toumpanakis D 

PROVIDER: S-EPMC12405914 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature