Opioid Timeliness in the Emergency Department and Hospitalizations for Acute Sickle Cell Pain.

ABSTRACT:

Importance

Guidelines for the timely emergency department (ED) administration of opioids for acute sickle cell disease (SCD) pain lack clear evidence showing associations with reduced hospitalizations.

Objective

To evaluate the associations between the timely administration of multiple opioid doses during uncomplicated SCD pain episodes in children and hospitalization.

Design, setting, and participants

This multisite cross-sectional study used data from the Pediatric Emergency Care Applied Research Network Registry. Included were 12 pediatric EDs from children's hospitals with comprehensive SCD centers across the US. ED visits by children younger than 19 years with uncomplicated SCD pain at any of the 12 sites between January 1, 2019, and December 31, 2021, were inclu

SUBMITTER: Gwarzo I 

PROVIDER: S-EPMC12406144 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature