A titanium redox-switch enables reversible C-C bond forming and splitting reactions.

ABSTRACT: Using an Earth-abundant transition metal to mediate formation and splitting of C-C σ-bonds, in response to electrical stimuli, constitutes a promising strategy to construct complex organic skeletons. Here, we showcase how [ ⁿ Bu₄N][N₃] reacts with an isocyanide adduct of a tetrahedral and high-spin Ti^II complex, [(Tp ^tBu,Me)TiCl] (1), to enact N-atom transfer, C-N bond formation, and C-C coupling, to form a dinuclear complex, [(Tp ^tBu,Me)Ti{AdN(N)C-C(N)NAd}Ti(Tp ^tBu,Me)] (3), with two Ti^III ions bridged by a disubstituted oxalimidamide ligand ( ⁿ Bu = n-butyl, Tp ^tBu,Me = hydrotris(3-tert-butyl-5-methylpyrazol-1-yl)borate, Ad

SUBMITTER: G Jafari M 

PROVIDER: S-EPMC12406152 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature