Dual Detection of Glucose Using Commercial Potassium Permanganate and Glucose Oxidase: Colorimetric and Absorbance-Based Approaches.

ABSTRACT: Accurate and accessible glucose detection is essential for clinical diagnostics, point-of-care testing, food safety, and biosensing applications. In this study, we present a simple, scalable, and dual-mode glucose sensor that integrates commercial potassium permanganate (KMnO₄) with glucose oxidase to enable sensitive and selective detection in the clinically critical range of 1-5 mM. Leveraging the strong oxidative power and distinct optical characteristics of KMnO₄, the sensor operates via both absorbance measurement at 400 nm and visual colorimetric analysis, displaying a clear color change from purple to pink and yellow upon reaction with glucose. The system achieves a low detection limit of 0.63 mM and demonstrates high specificity, effectively minimizing interfe

SUBMITTER: Hoang CNM 

PROVIDER: S-EPMC12406281 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature