Predicting White Matter Hyperintensity: Leveraging Portable MRI for Accessible Brain Health Screening.

ABSTRACT:

Background and purpose

Portable MRI (pMRI) has emerged as a cost-effective and accessible tool for the identification of white matter hyperintensities (WMH), an independent risk factor for stroke and dementia. Our objective was to confirm that pMRI can produce accurate WMH measurements and to develop and validate a risk model to predict WMH on pMRI for the purpose of identifying patients who may benefit from pMRI screening.

Materials and methods

The development (n = 143) and validation (n = 127) cohorts included patients without acute neurologic pathology who received a pMRI at a tertiary care hospital between May 2020 and July 2024. The development cohort included pMRIs collected as part of a prospective WMH screening pilot program in the emergency department.

SUBMITTER: Johnson IP 

PROVIDER: S-EPMC12406303 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature