Comorbidities in pregnant South African women living with HIV and associations with adverse birth outcomes: a prospective cohort study.

ABSTRACT:

Background

Despite improved health and survival due to lifelong antiretroviral therapy (ART), women living with HIV (WHIV) still face lower life expectancy, partly due to increased non-communicable disease (NCD) risk. Both HIV and NCDs are linked to adverse birth outcomes, yet data on their combined impact are limited. We investigated NCD burden by HIV status and compared adverse birth outcomes in pregnant WHIV only versus HIV-NCD comorbidity in Cape Town, South Africa.

Methods

Pregnant WHIV (n = 479) and without HIV (n = 510) were enrolled and prospectively followed for pregnancy outcome. Weight and height measurements were serially collected by a study nurse, and diagnoses of hypertension and diabetes mellitus (DM) were made by healthcare providers as part of routine care

SUBMITTER: Lehloa AJ 

PROVIDER: S-EPMC12406354 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature