The association between triglyceride glucose-waist height ratio index and cardiometabolic multimorbidity among Chinese middle-aged and older adults: a national prospective cohort study.

ABSTRACT:

Background

Cardiometabolic multimorbidity (CMM) imposes a progressively severe health burden worldwide. Triglyceride-glucose (TyG) index and waist-to-height ratio (WHtR), as indicators of insulin resistance and central adiposity, respectively, have been shown to be strongly associated with CMM. However, there is currently a lack of research combining the two for CMM risk assessment. This study aims to investigate the relationship between TyG-WHtR index and CMM.

Methods

This prospective cohort study analyzed data from Chinese adults aged ≥ 45 years participating in the 2011-2020 waves of the China Health and Retirement Longitudinal Study (CHARLS). We employed the Kaplan-Meier curves, multivariable Cox regression analysis, and restricted cubic spline (RCS) to examine the relat

SUBMITTER: Lv L 

PROVIDER: S-EPMC12406543 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature