The development and validation of postpartum hemorrhage prediction models for pregnancies with placenta previa totalis based on coagulation function indexes: a retrospective cohort study.

ABSTRACT:

Background

The objective of this study is to establish and validate models that can accurately predict postpartum hemorrhage (PPH) in women with placenta previa totalis prior to undertaking cesarean delivery.

Methods

A retrospective cohort study was conducted on 306 pregnancies with placenta previa totalis delivered between January 2011 and June 2022. The pregnancies were classified into two groups, PPH group and non-PPH group, based on bleeding volume and red blood cell transfusion. Clinical features and pre-operative coagulation function indexes were recorded. The entire cohort was randomly divided into a development cohort (n = 214) and a test cohort (n = 92). Least absolute shrinkage and selection operator (LASSO) was implemented to select significant predictors, followe

SUBMITTER: Hong S 

PROVIDER: S-EPMC12406593 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature