Lifetime Cannabis Use and Incident Hypertension: The Coronary Artery Risk Development in Young Adults (CARDIA) Study.

ABSTRACT:

Background

Observational evidence investigating associations between cannabis use and hypertension is inconsistent.

Methods

The association between cumulative lifetime cannabis use (cannabis-years) and incident hypertension was examined over 35 years in a sample of CARDIA study (Coronary Artery Risk Development in Young Adults) participants free of hypertension at baseline. Marginal structural models with inverse probability weighting were used to adjust for potential time-dependent confounding and censoring. Hazard ratios and 95% CIs were estimated using Cox proportional hazards regression. Sensitivity analyses included modeling cannabis-years using restricted cubic splines, stratifying the primary analyses by sex, race, alcohol and cigarette smoking, and evaluating an addi

SUBMITTER: Corroon J 

PROVIDER: S-EPMC12406996 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature