Trends in remission rates for rheumatoid arthritis in England and Wales: a population-level cohort study.

ABSTRACT:

Objectives

Considerable data support early treatment of RA to obtain disease remission. Data from the National Early Inflammatory Arthritis Audit (NEIAA) in England and Wales suggest that, despite recent improvements in referral-to-treatment times, remission rates remain unchanged. We investigated reasons for this disconnect by evaluating temporal trends, geographical variation and predictors of remission in individuals with new RA diagnoses.

Methods

An observational cohort study of individuals with RA was conducted using data from NEIAA (May 2018-April 2024). Temporal and geographical variation in remission rates (DAS28 < 2.6) were explored using interrupted time-series and case-mix-adjusted mixed-effects regression. Predictors of remission were assessed using multivariable

SUBMITTER: Alveyn E 

PROVIDER: S-EPMC12407236 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature