Patient Reported Outcome Measures for Rheumatoid Arthritis Disease Activity: Rasch measurement theory to identify items and domains.

ABSTRACT:

Objectives

Disease activity (DA) monitoring is a standard of care in RA. There is demand for achieving this through patient-reported outcome measures (PROMs). The aim of this study was to determine which items could be used to measure the construct of RA DA, by analysing legacy PROMs, using Rasch measurement theory (RMT) analyses.

Methods

Questionnaires including 10 legacy PROMs were sent to people with RA to create original and validation datasets. Items were grouped according to OMERACT domains and analysed using principal component analysis. Based on separate domain RMT analyses of the original dataset, domain-level testlets were assessed to determine which items measure the construct of RA DA. The result was then replicated in confirmatory factor analyses bifactor models

SUBMITTER: Pickles T 

PROVIDER: S-EPMC12407238 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature