A radiomics approach for predicting gait freezing in Parkinson's disease based on resting-state functional magnetic resonance imaging indices: A cross-sectional study.

ABSTRACT: JOURNAL/nrgr/04.03/01300535-202604000-00042/figure1/v/2025-06-30T060627Z/r/image-tiff Freezing of gait is a significant and debilitating motor symptom often observed in individuals with Parkinson's disease. Resting-state functional magnetic resonance imaging, along with its multi-level feature indices, has provided a fresh perspective and valuable insight into the study of freezing of gait in Parkinson's disease. It has been revealed that Parkinson's disease is accompanied by widespread irregularities in inherent brain network activity. However, the effective integration of the multi-level indices of resting-state functional magnetic resonance imaging into clinical settings for the diagnosis of freezing of gait in Parkinson's disease remains a challenge. Although previous studies have demo

SUBMITTER: Guo M 

PROVIDER: S-EPMC12407560 | biostudies-literature | 2026 Apr

REPOSITORIES: biostudies-literature