Association of sedentary behavior with atrial fibrillation-related biomarkers in a population with overweight or obesity.

ABSTRACT:

Background

Blood biomarkers can characterize the atrial substrate, helping to elucidate mechanisms of atrial fibrillation (AF) development. Understanding whether sedentary behavior affects AF-related biomarkers is key for future prevention strategies.

Methods

We studied 252 participants in PREDIMED-Plus, a multicenter randomized trial in Spain for the primary prevention of cardiovascular disease. A wrist-worn accelerometer was used to measure physical activity (PA) in a week at baseline and at least once during follow-up at years 3 and 5. Blood samples were collected at each time point to measure selected cardiovascular biomarkers: propeptide of procollagen type I, high-sensitivity (hs) troponin T (hsTnT), hs C-reactive protein, 3-nitrotyrosine, and N-terminal propeptide of

SUBMITTER: Li L 

PROVIDER: S-EPMC12407610 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature