Functional diversity of Arabidopsis late embryogenesis abundant proteins in response to changes in the physicochemical environment.

ABSTRACT: Some desiccation-tolerant organisms accumulate intrinsically disordered proteins (IDPs), such as Late Embryogenesis Abundant (LEA) proteins, which help protect other proteins from inactivation and/or aggregation during desiccation. Like other IDPs, LEA proteins adopt ensembles of extended conformations that shift in response to environmental changes. Desiccation causes dramatic changes in the cellular environment, but it is unclear how the structural malleability of LEAs is related to their protective function. In this work, we measured the in vitro protective function and structural sensitivity to changes in the environment of four Arabidopsis thaliana LEA proteins from different families. We found that all LEAs showed different protection efficiencies of the labile enzyme l

SUBMITTER: Palomino-Navarrete LD 

PROVIDER: S-EPMC12407985 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature