Beyond recombination: Exploring the impact of meiotic frequency on genome-wide genetic diversity.

ABSTRACT: An important aim of population genetics is to elucidate the processes affecting genetic diversity across regions of the genome and across species. Canonical population genetic models of sexually reproducing species define the rate of meiotic recombination in terms of the frequency of recombination events per site per sexual generation. This paper studies the interplay of several factors with respect to their effects on neutral genetic diversity in a facultatively sexual, diploid, unicellular species such as yeast. The relevant factors are the prevalence of meiosis versus mitosis, the recombination rate, and the selection and dominance coefficients at loci under positive selection. We assume that many generations of mitotic cell divisions are interspersed with episodes of sexual reproductio

SUBMITTER: Ollivier L 

PROVIDER: S-EPMC12408092 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature