Complete biosynthesis of salicylic acid from phenylalanine in plants.

ABSTRACT: Salicylic acid (SA) is a pivotal phytohormone for plant responses to biotic and abiotic stresses. Plants have evolved two pathways to produce SA: the isochorismate synthase and phenylalanine ammonia lyase (PAL) pathways¹. Whereas the isochorismate synthase pathway has been fully identified^2-4, the PAL pathway remains incomplete. Here we report the full characterization of the PAL pathway for SA biosynthesis via functional analysis of rice (Oryza sativa) SA-DEFICIENT GENE 1 (OSD1) to OSD4. The cinnamoyl-coenzyme A (CoA) ligase OSD1 catalyses the conversion of trans-cinnamic acid to cinnamoyl-CoA, which is subsequently transformed to benzoyl-CoA via the β-oxidative pathway in peroxisomes. The resulting benzoyl-CoA is further converted to benzyl benzoate by the peroxisom

SUBMITTER: Zhu B 

PROVIDER: S-EPMC12408352 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature